Green synthesis of ZnO nanoparticles using guava leaf extract and potential for biomedical applications

Authors

  • Kavya Prakash K. M. Author
  • Neeraja N. Author
  • Prakash V. Department of PG Studies & Research in Physics, Payyanur College, Kannur University, Edat Kannur, Kerala, 670327 Author

Keywords:

Zinc oxide; Guava leaf; XRD; Nanoparticles; SEM; Biosynthesis

Abstract

The conventional ways of creating metal oxide nanoparticles in biomedicine and pharmaceuticals have been replaced by environmentally friendly alternatives that do not require the use of chemical stabilizing and reducing agents. ZnO nanoparticles were synthesized in this study using Psidium guajava, a valuable herbal plant with medicinal potential that is commonly known as guava. In pharmaceutical formulations, bioactive components derived from medicinal plants are essential because they function as capping and reducing agents for metal ions during the creation of nanoparticles. Zinc oxide nanoparticles are produced when the phytochemicals in guava leaf extract undergo reduction/oxidation. The experiment was repeated with different precursor concentrations (3g, 4g, 5g, and 6g) to examine the effect of precursor molarity on the physical properties of the nanoparticles. Furthermore, a comparison was made between the average particle size of ZnO nanoparticles produced chemically and those produced through biosynthesis. X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS), and ultraviolet-visible spectroscopy (UV-Vis) were used to analyze the produced nanoparticles.

References

[1] Joy Sarkar, Manosij Ghosh, Anita Mukherjee, Dipankar Chattopadhyay, Krishnendu Acharya. Biosynthesis and safety evaluation of ZnO nanoparticles. Bioprocess Biosystem Eng. 2014; 37: 165–171.

[2] Arya Rajan, Elsa Cherian, G. Baskar. Biosynthesis of zinc oxide nanoparticles using Aspergillus fumigatus JCF and its antibacterial activity. International Journal of Modern Science and Technology. 2016; 1: 52–57.

[3] Rajeshkumar S, Venkat Kumar S, Arunachalam Ramaiah, Happy Agarwal, Lakshmi T, Selvaraj and Mohana Roopan. Biosynthesis of zinc oxide nanoparticles using Mangifera indica leaves and evaluation of their antioxidant and cytotoxic properties in lung cancer (A549) cells. Enzyme and Microbial Technology. 2018; 3: 42–50.

[4] Amin Boroumand Moghaddam, Mona Moniri, Susan Azizi, Raha Abdul Rahim, Arbakariya Bin Ariff, Wan Zuhainis Saad, Farideh Namvar, Mohammad Navaderi and Rosfarizan Mohamad. Biosynthesis of ZnO Nanoparticles by a New Pichia kudriavzevii Yeast Strain and Evaluation of Their Antimicrobial and Antioxidant Activities. Molecules. 2017; 22: 872.

[5] Tamanna Bhuyan, Kavita Mishra, Manika Khanuja, Ram Prasad and Ajit Varma. Biosynthesis of zinc oxide nanoparticles from Azadirachta indica for antibacterial and photocatalytic applications. Materials Science in Semiconductor Processing. 2015; 32: 55–61.

[6] Avnish Kumar Arora, Sarita Devi, Vivek Sheel Jaswal, Joginder Singh, Mayank Kinger, and Vishnu Dev Gupta. Synthesis and Characterization of ZnO Nanoparticles. Oriental Journal of Chemistry. 2014; 30: 1671–1679.

[7] Manjunatha RL, Usharani KV and Dhananjay Naik. Synthesis and characterization of ZnO nanoparticles: A review. Journal of Pharmacognosy and Phytochemistry. 2019; 8(3): 1095–1101.

[8] G. Xiong, U. Pal, J. G. Serrano, K. B. Ucer, and R. T. Williams. Photoluminescence and FTIR study of ZnO nanoparticles: the impurity and defect perspective. Phys. stat. sol. 2006; 10: 3577–3581. DOI: 10.1002/pssc.200672164.

[9] Harish Kumar and Renu Rani. Structural and Optical Characterization of ZnO Nanoparticles Synthesized by Microemulsion Route. International Letters of Chemistry. 2013; 14: 26–36.

[10] Abdol Aziz, R. A. Abd Karim, S. F. Ibrahim, and Sanuddin. Precursor Concentration Effect on Physicochemical Properties of Zinc Oxide Nanoparticle Synthesized with Banana Peel Extract. Key Engineering Materials. 2018; 797: 262–270.

[11] S. V. Elangovana, V. Chandramohanb, N. Sivakumar and T. S. Senthil. Synthesis and characterization of ZnO nanoparticles at different molarity concentrations for photocatalytic applications. Taylor & Francis. 2015; 3: 1–8. DOI: 10.1080/19443994.2015.1035340.

[12] P. N. Sibiya and M. J. Moloto. Effect of precursor concentration and pH on the shape and size of starch-capped silver selenide Nanoparticles. Chalcogenide Letters. 2014; 11: 577–588.

Downloads

Published

2026-08-15

How to Cite

Kavya Prakash K. M., Neeraja N., & Prakash V. (2026). Green synthesis of ZnO nanoparticles using guava leaf extract and potential for biomedical applications. Journal of Radiation, Environment and Climate, 1(1), 10-21. https://vaishakha.com/index.php/jrec/article/view/28

Similar Articles

You may also start an advanced similarity search for this article.